This article is intended to give you a glimpse of custom-made medicine, customized medicine, or personalized medicine. The benefits of personalized medicine, or PM as it is popularly abbreviated, has been proved by many. Such benefits have been discussed in scientific studies, European Commission reports, and those from different national governments and industry reports. From the analysis of NSCLC, breast cancer, ovarian cancer, and melanoma cases, it is clear patients stand to benefit from PM’s development in a wide variety of ways. The more significant among them are as follows:

The Targeted Response Rate Results Have Enhanced Efficacy

As per a paper released by the European Commission, it is much more probable that a patient will have the desired treatment outcome with personalized medicine. The experts from https://customcompounding.com.au/ explain this is since personalized medicine makes the therapies better targeted. Besides, PM also makes it possible for doctors to intervene at an earlier stage of the disease. They don’t longer need to do any trial and error therapies and prescribe the optimal medicines right from the start. Untargeted treatments are highly inefficient. Scientific studies have out that:

• 38% of patients suffering from depression
• 50% of arthritis patients
• 43% of diabetic patients
• 40% of asthma patients

Don’t respond too well to initial treatment. Through personalized medicine, there are a large number of variations in the medicine molecules. The more generous amount of information available at the disposal of physicians helps them assess which medicine would work best for a particular patient.

Additionally, the different types of molecular screening, including genetics, are of immense help in determining optimum dosage schedules or the medication combination that is best suited for a particular patient. In short, it should provide better healthcare by matching the benefits of the therapy with the patient’s unique needs.

Improvements in Overall Survival

Scientists have been able to identify the molecules that drive the growth of particular tumors. Such findings have, in turn, facilitated the development of new therapies. Cancer is one area where personalized medicine has progressed a lot. Let’s consider a meta-study that was carried out regarding PM’s role in many cancer types. The study included phase two clinical trials as per 570 studies involving 32,149 patients. The study compared the response rate, overall survival, and progression-free survival of patients with PM and those receiving more traditional therapies. The results have borne out the following facts:

• PM had higher response rates
• Better outcomes

The Case For PM In Breast Cancer

Before PM was introduced for breast cancer patients, doctors were not able to customize the therapies. They had a considerable amount of side effects. HER-2 positive patients were given adjuvant treatment. Studies found PM to reduce the condition recurrence by 50% approx with follow-up treatments for one to two and a half years. There is plenty of scientific literature that documents PM’s outstanding contribution to the significant improvement in mortality. In the EU, these mortality rates stood at 17.9 in every hundred thousand people. The 2012 figure stood at 15.2, and it is all set to go down further to 13.4 this year. In all, it should suffice to know that throughout the EU, the survival rates are going up for age-adjusted five-year survival rates.

Another interesting thing to note is that there has been quite a shift in the metastatic melanoma treatment landscape. This shift has been fueled by significant discoveries relating to oncogenic mutations, particularly in MAP kinase pathway controlling genes. This discovery has facilitated the development of PM treatments for melanoma.

Cut Down On Side Effects

It is possible to cut down on the side effects of many medical treatments by using genetic markers. Such markers make it possible to make the medication dosing more effective and according to the particular patient and their genetic forbearance. There are plenty of researchers out there who envision a great role for pharmacogenomics in identifying those responding and not responding to drugs. Not only that, but they also serve to prevent side effects and ensure optimum drug doses based on the particular patient.

In this context, it will be helpful to recollect the meta-study, which assesses grade three to four adverse effects. In non-medical parlance, this super study observed the severe and life-threatening side effects of drugs used to treat melanoma. The study found a significantly lesser amount of side effects of such treatments with anti-PD1 therapy than chemotherapy. Another survey of patients with urothelial carcinoma showed PM reduced side effects. It showed that pembrolizumab’s use reduced the frequency of side effects. The figures stood at 15% from the whopping 49.4% resulting from chemotherapy.

From all these facts, it is evident that the PM is all set to infuse a fresh breath of life in millions of people’s lives. People suffering from often fatal or at least severe health issues have a reason to cheer. Personalized medicine is effective in not only survival rates but also ensures a minimum amount of side effects. It is the new vista towards which medical science is moving and promises better lives and enhanced cures for health conditions.

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